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Teratogenicity assessment in pregnant rats receiving 0.2-4 mg/kg intramuscularly during days 6-15 of pregnancy found no effects on fetuses or organ development

This mechanism complements the angiogenic and proliferative effects of the peptide, ensuring that new cells not only form but also reach the locations where they are needed

Endocrinology 155 , 45914601 (2014)

As granulomas mature, they develop fibrous walls and experience a significant decrease in the number of vessels penetrating the structure, which hampers the penetration of anti-TB drugs into the necrotic and hypoxic areas of the granuloma, where M.tb persists [98, 99]